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Infettivologia pediatrica  

 Linea di ricerca

 

Infettivologia pediatrica

Influenza

Importanza clinica e socioeconomica delle infezioni da virus influenzali in età pediatrica

Studio della suscettibilità genetica dell’ospite alle complicanze dell’influenza

Analisi filogenetica dei nuovi virus influenzali circolanti

 

Infezioni da batteri invasivi

Epidemiologia, diagnosi, manifestazioni cliniche e terapia delle infezioni pneumococciche 

Epidemiologia, diagnosi, manifestazioni cliniche e terapia delle infezioni meningococciche 

 

Infezioni del sistema nervoso centrale

Terapia antibiotica nelle meningiti batteriche

Terapia antivirale nelle encefaliti

Utilizzo dei corticosteroidi nelle meningiti batteriche e nelle encefaliti

 

Tubercolosi

Epidemiologia della tubercolosi in età pediatrica e creazione del Registro Italiano della tubercolosi in pediatria

Sensibilità e specificità dei nuovi metodi diagnostici in età pediatrica

Trattamento della tubercolosi multiresistente nel bambino           

 

Infezione da HIV

Trasmissione verticale dell’infezione

Storia naturale dell’infezione in età pediatrica

Terapia antiretrovirale

Profilassi delle infezioni opportunistiche

Gestione dei problemi socio-assistenziali dei figli di donne HIV-sieropositive

 

Infezioni dell’ospite immunocompromesso

Epidemiologia delle infezioni virali nel bambino oncoematologico e nel bambino trapiantato

Gestione delle infezioni da catetere venoso centrale

Indicazioni all’antibioticoprofilassi

           

Infezioni rare ed emergenti

Malattia di Lyme in età pediatrica

Prevenzione e terapia delle infezioni nel bambino viaggiatore

Prevenzione e terapia delle infezioni nosocomiali in pediatria


 

 Sede operativa di svolgimento della linea di ricerca

 Laboratorio

c/o via Rugabella 4, Milano (4° piano)

tel. 02 57993946

email: laboratorio.principi@gmail.com

 

 Reparto

c/o Clinica Pediatrica De Marchi (2° e 3° piano)

tel. 02 55032473-2427

fax 02 55032427-2469

 

 Ambulatori

c/o Padiglione Regina Elena (2° piano)

tel 02 55034275

Fax 02 55034201

 

 

 Day Hospital/MAC

c/o Clinica Pediatrica De Marchi (piano terra)

tel 02 55032750

Fax 02 55032903

 

 

 Clinical Trial Unit

 

 

 

c/o Padiglione Regina Elena (2° piano)

tel 02 55034338

fax 02 55034201 

 Responsabile

 nome                            Susanna

 cognome                     Esposito

 tel                                 02 55032498

 fax                                02 50320206

 e-mail                          susanna.esposito@unimi.it

 Collaboratori

 Universitari

 Totale n. 1

 Ospedalieri

 Totale n. 6

 Assegnisti

 Totale n. 4

 Borsisti

 Totale n. 12

 Altre qualifiche

 Totale n.

 Parole chiave

1. Malattie infettive pediatriche

2. Infezioni respiratorie

3. Vaccini

4. Terapia infettiva

5. Malattie rare

 Pubblicazioni

 Anno 2013 (luglio 2013) – Elenco

Immune history shapes specificity of pandemic H1N1 influenza antibody responses.

Li Y, Myers JL, Bostick DL, Sullivan CB, Madara J, Linderman SL, Liu Q, Carter DM, Wrammert J, Esposito S, Principi N, Plotkin JB, Ross TM, Ahmed R, Wilson PC, Hensley SE.

J Exp Med. 2013 Jul 15

A roadmap for fever of unknown origin in children.

Rigante D, Esposito S.

Int J Immunopathol Pharmacol. 2013 Apr-Jun;26(2):315-26.

Pneumococcal Bacterial Load Colonization as a Marker of Mixed Infection in Children with Alveolar Community-Acquired Pneumonia and Respiratory Syncytial Virus or Rhinovirus Infection.

Esposito S, Zampiero A, Terranova L, Ierardi V, Ascolese B, Daleno C, Prada E, Pelucchi C, Principi N.

Pediatr Infect Dis J. 2013 Jun 5.

Healthcare transition in patients with rare genetic disorders with and without developmental disability: Neurofibromatosis 1 and williams-beuren syndrome.

Van Lierde A, Menni F, Bedeschi MF, Natacci F, Guez S, Vizziello P, Costantino MA, Lalatta F, Esposito S.

Am J Med Genet A. 2013 Jul;161(7):1666-74.

Vitamin D Supplementation Reduces the Risk of Acute Otitis Media in Otitis-Prone Children.

Marchisio P, Consonni D, Baggi E, Zampiero A, Bianchini S, Terranova L, Tirelli S, Esposito S, Principi N.

Pediatr Infect Dis J. 2013 May 20.

Is there a crossroad between infections, genetics, and Henoch-Schönlein purpura?

Rigante D, Castellazzi L, Bosco A, Esposito S.

Autoimmun Rev. 2013 May 15.

Peritoneal tuberculosis due to multidrug-resistant Mycobacterium tuberculosis.

Esposito S, Bosis S, Canazza L, Tenconi R, Torricelli M, Principi N.

Pediatr Int. 2013 Apr;55(2):e20-2.

The role of infection in Kawasaki syndrome.

Principi N, Rigante D, Esposito S.

J Infect. 2013 Jul;67(1):1-10.

Genome characterisation of enteroviruses 117 and 118: a new group within human enterovirus species C.

Piralla A, Daleno C, Scala A, Greenberg D, Usonis V, Principi N, Baldanti F, Esposito S; CAP-PRI Study Group.

PLoS One. 2013;8(4):e60641.

Influenza vaccination in children with cystic fibrosis.

Patria MF, Longhi B, Esposito S.

Expert Rev Vaccines. 2013 Apr;12(4):415-20.

Role of vitamin D in children with respiratory tract infection.

Esposito S, Baggi E, Bianchini S, Marchisio P, Principi N.

Int J Immunopathol Pharmacol. 2013 Jan-Mar;26(1):1-13.

Comparison of posterior pharyngeal wall and nasopharyngeal swabbing as a means of detecting the carriage of Neisseria meningitidis in adolescents.

Esposito S, Zampiero A, Terranova L, Montinaro V, Peves Rios W, Scala A, Ansuini V, Galeone C, Principi N.

Eur J Clin Microbiol Infect Dis. 2013 Mar 17.

A survey on features of allergic rhinitis in children.

Zicari AM, Indinnimeo L, De Castro G, Incorvaia C, Frati F, Dell'Albani I, Puccinelli P, Scolari M, Duse M; Pediatric SURF Study Group.

Curr Med Res Opin. 2013 May;29(5):415-20.

Full Genome Sequence of a Novel Human Enterovirus C (EV-C118) Isolated from Two Children with Acute Otitis Media and Community-Acquired Pneumonia in Israel.

Daleno C, Piralla A, Scala A, Baldanti F, Greenberg D, Principi N, Esposito S; CAP-PRI Study Group.

Genome Announc. 2013 Jan;1(1).

Dog and cat bite-associated infections in children.

Esposito S, Picciolli I, Semino M, Principi N.

Eur J Clin Microbiol Infect Dis. 2013 Aug;32(8):971-6.

Vitamin D and influenza vaccination.

Principi N, Esposito S.

Hum Vaccin Immunother. 2013 Feb 12;9(5).

DNA bacterial load in children with bacteremic pneumococcal community-acquired pneumonia.

Esposito S, Marchese A, Tozzi AE, Rossi GA, Da Dalt L, Bona G, Pelucchi C, Schito GC; Italian Pneumococcal CAP group, Principi N.

Eur J Clin Microbiol Infect Dis. 2013 Jul;32(7):877-81.

Recurrent lower respiratory tract infections in children: a practical approach to diagnosis.

Patria MF, Esposito S.

Paediatr Respir Rev. 2013 Mar;14(1):53-60.

Vaccine administration and the development of immune thrombocytopenic purpura in children.

Cecinati V, Principi N, Brescia L, Giordano P, Esposito S.

Hum Vaccin Immunother. 2013 Jan 16;9(5).

Impact of vitamin D administration on immunogenicity of trivalent inactivated influenza vaccine in previously unvaccinated children.

Principi N, Marchisio P, Terranova L, Zampiero A, Baggi E, Daleno C, Tirelli S, Pelucchi C, Esposito S.

Hum Vaccin Immunother. 2013 Jan 16;9(5).

Immunogenicity and safety of an investigational multicomponent, recombinant, meningococcal serogroup B vaccine (4CMenB) administered concomitantly with routine infant and child vaccinations: results of two randomised trials.

Vesikari T, Esposito S, Prymula R, Ypma E, Kohl I, Toneatto D, Dull P, Kimura A; EU Meningococcal B Infant Vaccine Study group.

Lancet. 2013 Mar 9;381(9869):825-35.

Debate around infection-dependent hemophagocytic syndrome in paediatrics.

Ansuini V, Rigante D, Esposito S.

BMC Infect Dis. 2013 Jan 16;13:15.

Pharmacotherapy for pneumococcal infections: an update.

Esposito S, Principi N.

Expert Opin Pharmacother. 2013 Jan;14(1):65-77.

Clinical relevance of Mycoplasma pneumoniae macrolide resistance in children.

Cardinale F, Chironna M, Chinellato I, Principi N, Esposito S.

J Clin Microbiol. 2013 Feb;51(2):723-4.

 

Implications of maternal vitamin D deficiency for the fetus, the neonate and the young infant.

Principi N, Bianchini S, Baggi E, Esposito S.

Eur J Nutr. 2013 Apr;52(3):859-67

A retrospective evaluation of microbiology of acute otitis media complicated by spontaneous otorrhea in children living in Milan, Italy.

Marchisio P, Bianchini S, Baggi E, Fattizzo M, Galeone C, Torretta S, Principi N, Esposito S.

Infection. 2013 Jun;41(3):629-35.

Macrolide-resistant Mycoplasma pneumoniae: its role in respiratory infection.

Principi N, Esposito S.

J Antimicrob Chemother. 2013 Mar;68(3):506-11.

A novel human enterovirus C (EV-C118) identified in two children hospitalised because of acute otitis media and community-acquired pneumonia in Israel.

Daleno C, Greenberg D, Piralla A, Scala A, Baldanti F, Principi N, Esposito S.

J Clin Virol. 2013 Feb;56(2):159-62.

Borrelia burgdorferi infection and Lyme disease in children.

Esposito S, Bosis S, Sabatini C, Tagliaferri L, Principi N.

Int J Infect Dis. 2013 Mar;17(3):e153-8.

Management of paediatric Lyme disease in non-endemic and endemic areas: data from the Registry of the Italian Society for Pediatric Infectious Diseases.

Esposito S, Baggi E, Villani A, Norbedo S, Pellegrini G, Bozzola E, Palumbo E, Bosis S, Nigro G, Garazzino S, Principi N; SITIP Lyme Disease Registry.

Eur J Clin Microbiol Infect Dis. 2013 Apr;32(4):523-9.

Habitual use of push and pull plastic bottle caps is more prevalent among children with recurrent acute otitis media.

Torretta S, Marchisio P, Cappadona M, Baggi E, Pignataro L.

Int J Pediatr Otorhinolaryngol. 2013 Jul;77(7):1179-82.

Permanent childhood hearing impairment: universal newborn hearing screening, PCHI management].

Martini A, Marchisio P, Bubbico L, Trevisi P, Perletti L.

Minerva Pediatr. 2013 Apr;65(2):231-50.

Panel 7: Treatment and comparative effectiveness research.

Marchisio P, Chonmaitree T, Leibovitz E, Lieberthal A, Lous J, Mandel E, McCormick D, Morris P, Ruohola A.

Otolaryngol Head Neck Surg. 2013 Apr;148(4 Suppl):E102-21.

Topographic distribution of biofilm-producing bacteria in adenoid subsites of children with chronic or recurrent middle ear infections.

Torretta S, Drago L, Marchisio P, Gaffuri M, Clemente IA, Pignataro L.

Ann Otol Rhinol Laryngol. 2013 Feb;122(2):109-13.

Nasopharyngeal fiberendoscopy in children: a diagnostic challenge in current clinical practice: how we do it.

Torretta S, Marchisio P, Cappadona M, Baggi E, Pignataro L.

Int J Pediatr Otorhinolaryngol. 2013 May;77(5):747-51.

Recurrences in chronic tonsillitis substained by tonsillar biofilm-producing bacteria in children. Relationship with the grade of tonsillar hyperplasy.

Torretta S, Drago L, Marchisio P, Cappadona M, Rinaldi V, Nazzari E, Pignataro L.

Int J Pediatr Otorhinolaryngol. 2013 Feb;77(2):200-4.

Anemic nevus in neurofibromatosis type 1.

Tadini G, Brena M, Pezzani L, Gelmetti C, Santagada F, Boldrini MP.

Dermatology. 2013;226(2):115-8.

Nevoid follicular mucinosis: a new type of hair follicle nevus.

Tadini G, Boldrini MP, Brena M, Pezzani L, Marchesi L, Rongioletti F.

J Cutan Pathol. 2013 Apr 11.

X-linked reticulate pigmentary disorder with systemic manifestations: a new family and review of the literature.

Pezzani L, Brena M, Callea M, Colombi M, Tadini G.

Am J Med Genet A. 2013 Jun;161(6):1414-20.

Papular Epidermal Nevus with "Skyline" Basal Cell Layer (PENS) Following a Blaschko Linear Pattern.

Faure E, Tadini G, Brena M, Restano Cassulini L.

Pediatr Dermatol. 2013 Apr 19.

Ectodermal dysplasias: the p63 tail.

Tadini G, Santagada F, Brena M, Pezzani L, Nannini P.

G Ital Dermatol Venereol. 2013 Feb;148(1):53-8.

Unraveling the mystery of the disorder of keratinization: the path of syndromic ichthyoses.

Pezzani L, Brena M, Santagada F, Faure E, Tadini G.

G Ital Dermatol Venereol. 2013 Feb;148(1):1-12.

A novel mosaic NSD1 intragenic deletion in a patient with an atypical phenotype.

Castronovo C, Rusconi D, Crippa M, Giardino D, Gervasini C, Milani D, Cereda A, Larizza L, Selicorni A, Finelli P.

Am J Med Genet A. 2013 Mar;161(3):611-8.

 IF: 150

 Anno 2012 - Elenco

Principi N, Bianchini S, Baggi E, Esposito S. No evidence for the effectiveness of systemic corticosteroids in acute pharyngitis, community-acquired pneumonia and acute otitis media. Eur J Clin Microbiol Infect Dis. 2012 Sep 21.

Marchese A, Esposito S, Barbieri R, Bassetti M, Debbia E. Does the adoption of EUCAST susceptibility breakpoints affect the selection of antimicrobials to treat acute community-acquired respiratory tract infections? BMC Infect Dis. 2012 Aug 6;12:181

Esposito S, Bosis S, Morlacchi L, Baggi E, Sabatini C, Principi N. Can infants be protected by means of maternal vaccination? Clin Microbiol Infect. 2012 Jun 5.

Esposito S, Tagliabue C, Tagliaferri L, Semino M, Longo MR, Principi N. Preventing influenza in younger children. Clin Microbiol Infect. 2012 Jun 5. 

Esposito S, Daleno C, Baggi E, Ciarmoli E, Lavizzari A, Pierro M, Semino M, Groppo M, Scala A, Terranova L, Galeone C, Principi N. Circulation of different rhinovirus groups among children with lower respiratory tract infection in Kiremba, Burundi. Eur J Clin Microbiol Infect Dis. 2012 Jul 12

Esposito S, Semino M, Picciolli I, Principi N. Should corticosteroids be used in bacterial meningitis in children? Eur J Paediatr Neurol. 2012 Jul 10.

Esposito S, Preti V, Consolo S, Nazzari E, Principi N. Adenovirus 36 infection and obesity. J Clin Virol. 2012 Oct;55(2):95-100. Epub 2012 Jul 6.

Chiappini E, Venturini E, Principi N, Longhi R, Tovo PA, Becherucci P, Bonsignori F, Esposito S, Festini F, Galli L, Lucchesi B, Mugelli A, de Martino M; Writing Committee of the Italian Pediatric Society Panel for the Management of Fever in Children. Update of the 2009 Italian Pediatric Society Guidelines about management of fever in children.  Clin Ther. 2012 Jul;34(7):1648- 653.e3. Epub 2012 Jun 27.

Guez S, Chiarelli G, Menni F, Salera S, Principi N, Esposito S. Severe vitamin B12 deficiency in an exclusively breastfed 5-month-old Italian infant born to a mother receiving multivitamin supplementation during pregnancy. BMC Pediatr. 2012 Jun 24;12:85.

Principi N, Esposito S. Diagnosis and therapy of tuberculous meningitis in children.  Tuberculosis (Edinb). 2012 Sep;92(5):377-83. Epub 2012 Jun 20

 

Esposito S, Picciolli I, Semino M, Principi N. Steroids and childhood encephalitis. Pediatr Infect Dis J. 2012 Jul;31(7):759-60.

Chiappini E, Principi N, Mansi N, Serra A, De Masi S, Camaioni A, Esposito S, Felisati G, Galli L, Landi M, Speciale AM, Bonsignori F, Marchisio P, de Martino M; Italian Panel on the management of Pharyngitis in Children. Management of acute pharyngitis in children: summary of the Italian National Institute of Health guidelines.  Clin Ther. 2012 Jun;34(6):1442-1458.e2.

Esposito S, Molteni CG, Zampiero A, Baggi E, Lavizzari A, Semino M, Daleno C, Groppo M, Scala A, Terranova L, Miozzo M, Pelucchi C, Principi N. Role of polymorphisms of toll-like receptor (TLR) 4, TLR9, toll-interleukin 1 receptor domain containing adaptor protein (TIRAP) and FCGR2A genes in malaria susceptibility and severity in Burundian children.  Malar J. 2012 Jun 12;11:196.

Cecinati V, Brescia L, Tagliaferri L, Giordano P, Esposito S. Catheter-related infections in pediatric patients with cancer. Eur J Clin Microbiol Infect Dis. 2012 Jun 3.

Orlando G, Tanzi E, Chatenoud L, Gramegna M, Rizzardini G, Antonacci MC, Arcidiacono I, Bertuccio P, Bianchi S, Boero V, Cambiè G, Cetin I, Esposito S, Falchetti M, Fasolo MM, Galli C, Bertazzoli E, Lunghi G, Matteelli A, Tisi G, Zanchetta N, Zuccotti G. Rationale and design of a multicenter prospective cohort study for the eVALuation and monitoring of HPV Infections and relATEd cervical diseases in high-risk women (VALHIDATE study).  BMC Cancer. 2012 May 30;12(1):204.

Esposito S, Cohen R, Domingo JD, Pecurariu OF, Greenberg D, Heininger U, Knuf M, Lutsar I, Principi N, Rodrigues F, Sharland M, Spoulou V, Syrogiannopoulos GA, Usonis V, Vergison A, Schaad UB. Antibiotic therapy for pediatric community-acquired pneumonia: do we know when, what and for how long to treat?  Pediatr Infect Dis J. 2012 Jun;31(6):e78-85.

Chiappini E, Galli L, Tovo PA, Gabiano C, Lisi C, Giacomet V, Bernardi S, Esposito S, Rosso R, Giaquinto C, Badolato R, Guarino A, Maccabruni A, Masi M, Cellini M, Salvini F, Di Bari C, Dedoni M, Dodi I, de Martino M; Italian Register for HIV infection in children. Antiretroviral use in Italian children with perinatal HIV infection over a 14-year period.  Acta Paediatr. 2012 Jul;101(7):e287-95. doi: 10.1111/j.1651-2227.2012.02675.x. Epub 2012 Apr 4.

Menni F, Testa S, Guez S, Chiarelli G, Alberti L, Esposito S. Neonatal atypical hemolytic uremic syndrome due to methylmalonic aciduria and homocystinuria. Pediatr Nephrol. 2012 Aug;27(8):1401-5. Epub 2012 Mar 25.

Esposito S, Marchese A, Tozzi AE, Rossi GA, Da Dalt L, Bona G, Pelucchi C, Schito GC, Principi N; Italian Pneumococcal CAP Group. Bacteremic pneumococcal community-acquired pneumonia in children less than 5 years of age in Italy. Pediatr Infect Dis J. 2012 Jul;31(7):705-10.

Esposito S, Principi N Unsolved problems in the approach to pediatric community-acquired pneumonia. Curr Opin Infect Dis. 2012 Jun;25(3):286-91.

Principi N, Esposito S, Use of the 13-valent pneumococcal conjugate vaccine in infants and young children. Expert Opin Biol Ther. 2012 May;12(5):641-8. Epub 2012 Mar 7.

Porta A, Hsia Y, Doerholt K, Spyridis N, Bielicki J, Menson E, Tsolia M, Esposito S, Wong IC, Sharland M. Comparing neonatal and paediatric antibiotic prescribing between hospitals: a new algorithm to help international benchmarking. J Antimicrob Chemother. 2012 May;67(5):1278-86. Epub 2012 Feb 29.

Torretta S, Marchisio P, Drago L, Baggi E, De Vecchi E, Garavello W, Nazzari E, Pignataro L, Esposito S. Nasopharyngeal biofilm-producing otopathogens in children with nonsevere recurrent acute otitis media. Otolaryngol Head Neck Surg. 2012 Jun;146(6):991-6. Epub 2012 Feb 21.

 

Esposito S, Daleno C, Prunotto G, Scala A, Tagliabue C, Borzani I, Fossali E, Pelucchi C, Principi N. Impact of viral infections in children with community-acquired pneumonia: results of a study of 17 respiratory viruses.  Influenza Other Respi Viruses. 2012 Feb 13. doi: 10.1111/j.1750-2659.2012.00340.x.

Ferrera G, Cuccia M, Mereu G, Icardi G, Bona G, Esposito S, Federico M, Messier M, Kuriyakose S, Hardt K. Booster vaccination of pre-school children with reduced-antigen-content diphtheria-tetanus-acellular pertussis-inactivated poliovirus vaccine co-administered with measles-mumps-rubella-varicella vaccine: A randomized, controlled trial in children primed according to a 2+1 schedule in infancy. Hum Vaccin Immunother. 2012 Mar 1;8(3).

Gossger N, Snape MD, Yu LM, Finn A, Bona G, Esposito S, Principi N, Diez-Domingo J, Sokal E, Becker B, Kieninger D, Prymula R, Dull P, Ypma E, Toneatto D, Kimura A, Pollard AJ; European MenB Vaccine Study Group. Immunogenicity and tolerability of recombinant serogroup B meningococcal vaccine administered with or without routine infant vaccinations according to different immunization schedules: a randomized controlled trial.  JAMA. 2012 Feb 8;307(6):573-82.

Marchisio P, Baggi E, Bianchini S, Principi N, Esposito S. Clinical and socioeconomic impact of pediatric seasonal and pandemic influenza. Hum Vaccin Immunother. 2012 Jan 1;8(1):17-20. Epub 2012 Jan 1

Esposito S. Special focus: influenza vaccines. Hum Vaccin Immunother. 2012 Jan 1;8(1):6. Epub 2012 Jan 1.

Cecinati V, Brescia L, Esposito S. Thrombocytosis and infections in childhood. Pediatr Infect Dis J. 2012 Jan;31(1):80-1.

Königs C, Feiterna-Sperling C, Esposito S, Viscoli C, Rosso R, Kakuda TN, Leemans R, Peeters M, Mack R, Peeters I, Sinha R, Boven K, Giaquinto C. Pharmacokinetics and short-term safety and tolerability of etravirine in treatment-experienced HIV-1-infected children and adolescents. AIDS. 2012 Feb 20;26(4):447-55.

Dell'Era L, Corona F, Daleno C, Scala A, Principi N, Esposito S. Immunogenicity, safety and tolerability of MF59-adjuvanted seasonal influenza vaccine in children with juvenile idiopathic arthritis. Vaccine. 2012 Jan 20;30(5):936-40.

Esposito S, Daleno C, Tagliabue C, Scala A, Tenconi R, Borzani I, Fossali E, Pelucchi C, Piralla A, Principi N. Impact of rhinoviruses on pediatric community-acquired pneumonia. Eur J Clin Microbiol Infect Dis. 2012 Jul;31(7):1637-45. Epub 2011 Nov 29.

Tagliaferri L, Prunotto G, Hakizimana J, Peves Rios W, Pelucchi C, Principi N, Esposito S. Knowledge of malaria among women of Burundi and its impact on the incidence of the disease. J Trop Pediatr. 2012 Aug;58(4):258-62.

Antonova EN, Rycroft CE, Ambrose CS, Heikkinen T, Principi N. Burden of paediatric influenza in Western Europe: a systematic review. BMC Public Health. 2012 Nov 12;12(1):968.

Daleno C, Greenberg D, Piralla A, Scala A, Baldanti F, Principi N, Esposito S. A novel human enterovirus C (EV-C118) identified in two children hospitalised because of acute otitis media and community-acquired pneumonia in Israel. J Clin Virol. 2012 Nov 12. pii: S1386-6532(12)00394-0.

Esposito, S., Marchisio, P., Tenconi, R., Tagliaferri, L., Albertario, G., Patria, M.F., Principi, N. Diagnosis of acute rhinosinusitis. Pediatric Allergy and Immunology 2012 23 (SUPPL.22) pp. 17-19 

Esposito S, Preti V, Nazzari E, Consolo S, Principi N. Is there a link between infection due to adenovirus 36 and childhood obesity? Pediatr Infect Dis J. 2012 Nov;31(11):1184-6.

Bosis S. Semino M. Picciolli I. Pinzani R. Genitori L. Principi N. Esposito S. Meningitis complicated by subdural empyema and deafness caused by pneumoccoccal serotype 7F in a 17-month-old child: A case report  Journal of Preventive Medicine and Hygiene 2012 53 (2) , pp. 98-100

Matteo Gelardi, Paola Marchisio, Davide Caimmi, Cristoforo Incorvaia, Giada Albertario, Sonia Bianchini, Silvia Caimmi, Camilla Celani, Susanna Esposito, Miriam Fattizzo, Maria Luisa Fiorella, Franco Frati, Elena Labo, Gualtiero Leo, Amelia Licari, Alessia Marseglia, Elena Piacentini, Lorenzo Pignataro, Nicola Quaranta, Rossana Tenconi, Sara Torretta, Gian Luigi Marseglia Nicola Principi. Pathophysiology, favoring factors, and associated disorders in otorhinosinusology  Pediatric Allergy and Immunolog 2012 23 (SUPPL.22) , pp. 5-16

Dell'Era, L., Corona, F., Defilippi, A.C., Principi, N., Esposito, S., Esposito, A.   Systemic lupus erythematosus presenting with pulmonary thromboembolism in a 15-year-old girl  2012   Rheumatology International 32 (9) , pp. 2925-2928

Esposito, S., Marchisio, P., Montinaro, V., Bianchini, S., Weverling, G.J., Pariani, E., Amendola, A.,Fabiano, V., Pivetti, V., Zanetti, A., Zuccotti, G.V.  The immunogenicity and safety of a single 0.5 mL dose of virosomal subunit influenza vaccine administered to unprimed children aged ≥6 to <36 months: Data from a randomized, Phase III study     Vaccine 30  2012 pp. 7005-7012

Menni, F., Chiarelli, G., Sabatini, C., Principi, N., Esposito, S. Vaccination in children with inborn errors of metabolism. Vaccine  2012  Nov 26;30(50):7161-4

Piralla, A., Daleno, C., Pariani, E., Conaldi, P., Esposito, S., Zanetti, A., Baldanti, F.  Virtual quantification of influenza A virus load by real-time RT-PCR Journal of Clinical Virology 2012 Article in Press

Esposito, S., Baggi, E., Villani, A., Norbedo, S., Pellegrini, G., Bozzola, E., Palumbo, E., (), Principi, N.  Management of paediatric Lyme disease in non-endemic and endemic areas: data from the Registry of the Italian Society for Pediatric Infectious Diseases  2012   European Journal of Clinical Microbiology and Infectious Diseases , pp. 1-7   Article in Press

Drago L, De Vecchi E, Torretta S, Mattina R, Marchisio P, Pignataro L. Biofilm formation by bacteria isolated from upper respiratory tract before and after adenotonsillectomy. APMIS. 2012; 120:410-416.

Taylor S, Marchisio P,  Vergison A, Harriague J,  Hausdorff WP, Haggard M. Impact of Pneumococcal Conjugate Vaccination on Otitis Media: A Systematic Review. Clinical Infectious Diseases 2012; 54(12):1765-73.

P. Capaccio, P.E. Sigismund, N. Luca, P. Marchisio, L. Pignataro. Modern management of juvenile recurrent parotitis - J Laryngol Otol. 2012 Dec;126(12):1254-60

Marchisio P, Cantarutti L, Sturkenboom M, Girotto S, Picelli G, Dona D, Scamarcia A, Villa M, Giaquinto C. Burden of acute otitis media in primary care pediatrics in Italy: a secondary data analysis from the Pedianet database. BMC Pediatr. 2012 Nov 29;12(1):185.

Torretta S, Drago L, Marchisio P, Cappadona M, Rinaldi V, Nazzari E, Pignataro L.Recurrences in chronic tonsillitis substained by tonsillar biofilm-producing bacteria in children. Relationship with the grade of tonsillar hyperplasy. Int J Pediatr Otorhinolaryngol. 2012 Nov 5. pii: S0165-5876(12)00589-7

Milani D, Bedeschi MF, Iascone M, Chiarelli G, Cerutti M, Menni F. De Novo Deletion of 1q31.1-q32.1 in a Patient with Developmental Delay and Behavioral Disorders. Cytogenet Genome Res. 2012;136(3):167-70. Epub 2012 Mar 7

Esposito S, Molteni CG, Giliani S, Mazza C, Scala A, Tagliaferri L, Pelucchi C, Fossali E, Plebani A, Principi N. Toll-like receptor 3 gene polymorphisms and severity of pandemic A/H1N1/2009 influenza in otherwise healthy children. Virol J. 2012 Nov 15;9:270.

Marchisio P, Bianchini S, Baggi E, Fattizzo M, Galeone C, Torretta S, Principi N, Esposito S. A retrospective evaluation of microbiology of acute otitis media complicated by spontaneous otorrhea in children living in Milan, Italy. Infection. 2012 Dec 5.

Patria MF, Tenconi R, Esposito S. Efficacy and safety of influenza vaccination in children with asthma. Expert Rev Vaccines. 2012 Apr;11(4):461-8.

Principi N, Baggi E, Esposito S. Prevention of acute otitis media using currently available vaccines. Future Microbiol. 2012 Apr;7(4):457-65.

Esposito S, Montinaro V, Bosis S, Tagliabue C, Baggi E, Principi N. Recommendations for the use of influenza vaccine in pediatrics.  Hum Vaccin Immunother. 2012 Jan 1;8(1):102-6. Epub 2012 Jan 1.

Principi N, Esposito S. Adjuvanted influenza vaccines. Hum Vaccin Immunother. 2012 Jan 1;8(1):59-66. Epub 2012 Jan 1.

Esposito S, Montinaro V, Groppali E, Tenconi R, Semino M, Principi N. Live attenuated intranasal influenza vaccine. Hum Vaccin Immunother. 2012 Jan 1;8(1):76-80. Epub 2012 Jan 1.

Marchisio P, Varricchio A, Baggi E, Bianchini S, Capasso ME, Torretta S, Capaccio P, Gasparini C, Patria F, Esposito S, Principi N. Hypertonic saline is more effective than normal saline in seasonal allergic rhinitis in children. Int J Immunopathol Pharmacol. 2012 Jul-Sep;25(3):721-30.

Esposito S, Fumagalli M, Principi N  Immunogenicity, safety and tolerability of vaccinations in premature infants. Expert Rev Vaccines. 2012 Oct;11(10):1199-209.

ESCMID Sore Throat Guideline Group, Pelucchi C, Grigoryan L, Galeone C, Esposito S, Huovinen P, Little P, Verheij T. ESCMID Guideline for the management of acute sore throat. Clin Microbiol Infect. 2012 Apr;18 Suppl 1:1-28.

Azzari C, Moriondo M, Cortimiglia M, Valleriani C, Canessa C, Indolfi G, Ricci S, Nieddu F, de Martino M, Resti M  Italian group for the study of Invasive Pneumococcal Disease. Potential serotype coverage of three pneumococcal conjugate vaccines against invasive pneumococcal infection in Italian children. Vaccine. 2012 Mar 30;30(16):2701-5.

Principi N., Esposito S.,Childhood immunisation with conjugate vaccines and prevention of pneumonia THORAX 2012; 67(1): 83-84.

Esposito S. Management of community-acquired pneumonia in infants and children older than 3 months. Clin Infect Dis. 2012 Mar;54(6):884-5; author reply 885. Epub 2012 Jan 30. Daleno, C., Piralla, A., Usonis, V., Scala, A., Ivaskevicius, R., Baldanti, F., Principi, N., Esposito, S. Novel human enterovirus C infection in child with community-acquired pneumonia   Emerging Infectious Diseases 2012 18 (11) , pp. 1913-1915

Esposito S. Use of live attenuated influenza vaccine in individuals with asthma or a history of wheezing. Thorax 2012 Oct; 67(10) pp 925-926

Esposito S., Principi N., Necrotising pneumonia, pneumatoceles and pneumococcus THORAX Oct 2012 67 (10) 925-926.

Taylor S., Marchisio P., Vergison A., Hausdorff WP., Haggard M., Pneumococcal Conjugate Vaccines and Otitis Media, Int J of Otolaryngol 2012;2012:764573

 IF: 257

 Anno 2011 – Elenco

Torretta S, Marchisio P, ESPOSITO S, Cappadona M, Fattizzo M, Pignataro L. Diagnostic accuracy of the nasal obstruction index in detecting adenoid hypertrophy in children without allergy. International Journal of Pediatric Otorhinolaryngology 2011; 75: 57-61. ESPOSITO S, Meregalli E, Daleno C, Ghio L, Tagliabue C, Valzano A, Serra D, Galeone C, Edefonti A, Principi N. An open-label, randomized clinical trial assessing immunogenicity, safety and tolerability of pandemic influenza A/H1N1 MF59-adjuvanted vaccine administered sequentially or simultaneously with seasonal virosomal-adjuvanted influenza vaccine to paediatric kidney transplant recipients. Nephrology Dialysis Transplantation 2011; 26: 2018-2024.

ESPOSITO S, Salice P, Bosis S, Ghiglia S, Tremolati E, Tagliabue C, Gualtieri L, Barbier P, Galeone C, Marchisio P, Principi N. Altered cardiac rhythm in infants with bronchiolitis and respiratory syncytial virus infection. BMC Infectious Disease 2010; 10: 305. 

Principi N, ESPOSITO S. Management of severe community-acquired pneumonia of children in developing and developed countries. Thorax 2011; 66: 815-822.   

Esposito S, D'Angelo E, Daleno C, Peia F, Scala A, Serra D, Mirra N, Galeone C, Principi N. Immunogenicity, safety and tolerability of monovalent 2009 pandemic influenza A/H1N1 MF59-adjuvanted vaccine in patients with β-thalassemia major. Vaccine 2010; 28:7825-7828.

ESPOSITO S, Azzari C, Bartolozzi G, Fara GM, Giovanetti F, Lo Giudice M, Galeone C, Ciofi degli Atti M; Italian Society of Pediatric Allergy and Immunology. Knowledge of vaccination of allergic children among Italian primary care pediatricians, hospital pediatricians and pediatric residents. Vaccine 2010; 28: 7569-7575.

ESPOSITO S, Tagliaferri L, Daleno C, Valzano A, Picciolli I, Tel F, Prunotto G, Serra D, Galeone C, Plebani A, Principi N. Pandemic influenza A/H1N1 vaccine administered sequentially or simultaneously with seasonal influenza vaccine to HIV-infected children and adolescents. Vaccine 2011; 29: 1677-1682.

Esposito S, Birlutiu V, Jarcuska P, Perino A, Man SC, Vladareanu R, Meric D, Dobbelaere K, Thomas F, Descamps D. Immunogenicity and safety of human papillomavirus-16/18 AS04-adjuvanted vaccine administered according to an alternative dosing schedule compared with the standard dosing schedule in healthy women aged 15 to 25 years: results from a randomized study. Pediatric Infectious Disease Journal 2011; 30: e49-e55.

Andabaka T, Globočnik T, Vukelić D, Esposito S, Baršić B. Parental administration of antipyretics to children with upper respiratory tract infections without consultation with a physician. Croatian Medical Journal 2011; 52: 48-54.

Esposito S, Brivio A, Tagliabue C, Galeone C, Tagliaferri L, Serra D, Foà M, Patria MF, Marchisio P, Principi N. Knowledge of oxygen administration, aerosol medicine, and chest physiotherapy among pediatric healthcare workers in Italy. Journal of Aerosol Medicine & Pulmonary Drug Delivery 2011; 24: 149-156.

Principi N, Esposito S, Marchisio P. Present and future of influenza prevention in pediatrics. Expert Opinion Biological Therapy 2011; 11: 641-653.

Esposito S, Tagliabue C, Bosis S, Principi N. Levofloxacin for the treatment of Mycoplasma pneumoniae-associated meningoencephalitis in childhood. International Journal of Antimicrobial Agents 2011; 37: 472-475.

Chironna M, Sallustio A, Esposito S, Perulli M, Chinellato I, Di Bari C, Quarto M, Cardinale F. Emergence of macrolide-resistant strains during an outbreak of Mycoplasma pneumoniae infections in children. Journal of Antimicrobial Chemotherapy 2011; 66: 734-747.

Esposito S, Cantarutti L, Molteni CG, Daleno C, Scala A, Tagliabue C, Pelucchi C, Giaquinto C, Principi N. Clinical manifestations and socio-economic impact of influenza among healthy children in the community. Journal of Infection 2011; 62: 379-387.

Patria MF, Guez S, Balzani A, Esposito S. An unusual enlarged thymus. Archives of Disease in Childhood 2011; 96: 475.

Esposito S, Pugni L, Daleno C, Ronchi A, Valzano A, Serra D, Mosca F, Principi N. Influenza A/H1N1 MF59-adjuvanted vaccine in preterm and term children aged 6 to 23 months. Pediatrics 2011; 127: e1161-e1168.

Dell' Era L, Esposito S, Corona F, Principi N. Vaccination of children and adolescents with rheumatic diseases. Rheumatology (Oxford) 2011; 50: 1358-1365.

Marchese A, Esposito S, Coppo E, Rossi GA, Tozzi A, Romano M, Da Dalt L, Schito GC, Principi N. Detection of Streptococcus pneumoniae and identification of pneumococcal serotypes by real-time polymerase chain reaction using blood samples from Italian children ≤ 5 years of age with community-acquired pneumonia. Microbial Drug Resistance 2011; 17: 419-424.

Esposito S, Marchisio P, Tenconi R, Principi N. Antibiotic treatment of acute otitis media in pediatrics. Future Microbiology 2011; 6: 485-488.

Marchisio P, Bianchini S, Galeone C, Baggi E, Rossi E, Albertario G, Torretta S, Pignataro L, Esposito S, Principi N. Use of complementary and alternative medicine in children with recurrent acute otitis media in Italy. International Journal of Immunopathology & Pharmacology 2011; 24: 441-449.

Torretta S, Marchisio P, Esposito S, Garavello W, Cappadona M, Clemente IA, Pignataro L. Exhaled nitric oxide levels in children with chronic adenotonsillar disease. International Journal of Immunopathology & Pharmacology 2011; 24: 471-480.

Esposito S, Daleno C, Baldanti F, Scala A, Campanini G, Taroni F, Fossali E, Pelucchi C, Principi N. Viral shedding in children infected by pandemic A/H1N1/2009 influenza virus. Virology Journal 2011; 8:349.

Garazzino S, Krzysztofiak A, Esposito S, Castagnola E, Plebani A, Galli L, Cellini M, Lipreri R, Scolfaro C, Bertaina C, Calitri C, Bozzola E, Lancella L, Quondamcarlo A, Bosis S, Pugni L, Losurdo G, Soresina A, De Gaudio M, Mariotti I, Mancini L, Gabiano C, Tovo PA. Use of linezolid in infants and children: a retrospective multicentre study of the Italian Society for Paediatric Infectious Diseases. Journal of Antimicrobial Chemotherapy 2011; 66: 2393-2397.

Tagliabue C, Techasaensiri C, Torres JP, Katz K, Meek C, Kannan TR, Coalson JJ, Esposito S, Principi N, Leff R, Baseman JB, Hardy RD. Efficacy of increasing dosages of clarithromycin for treatment of experimental Mycoplasma pneumoniae pneumonia. Journal of Antimicrobial Chemotherapy 2011; 66: 2323-2329.

Esposito S, Principi N. Different influenza vaccine formulations and adjuvants for childhood influenza vaccination. Vaccine 2011; 29: 7535-7541.

Esposito S, Molteni CG, Daleno C, Tagliabue C, Picciolli I, Scala A, Pelucchi C, Fossali E, Principi N. Impact of pandemic A/H1N1/2009 influenza on children and their families: comparison with seasonal A/H1N1 and A/H3N2 influenza viruses. Journal of Infection 2011; 63: 300-307.

Esposito S, Daleno C, Picciolli I, Tagliaferri L, Scala A, Prunotto G, Montinaro V, Galeone C, Principi N. Immunogenicity and safety of intradermal influenza vaccine in children. Vaccine 2011; 29: 7606-7610.

Principi N, Esposito S. Universal protein vaccines against Neisseria meningitidis serogroup B, Streptococcus pneumoniae and influenza. Human Vaccines 2011; 7: 905-912.

Gatto F, Cassina G, Broccolo F, Morreale G, Lanino E, Di Marco E, Vardas E, Bernasconi D, Buttò S, Principi N, Esposito S, Scarlatti G, Lusso P, Malnati MS. A multiplex calibrated real-time PCR assay for quantitation of DNA of EBV-1 and 2. Journal of Virological Methods 2011; 178: 98-105.

Lutsar I, Trafojer UM, Heath PT, Metsvaht T, Standing J, Esposito S, de Cabre VM, Oeser C, Aboulker JP; NeoMero Consortium. Meropenem vs standard of care for treatment of late onset sepsis in children of less than 90 days of age: study protocol for a randomised controlled trial. Trials 2011; 12:215.

Esposito S, Tagliabue C, Picciolli I, Semino M, Sabatini C, Consolo S, Bosis S, Pinzani R, Principi N. Procalcitonin measurements for guiding antibiotic treatment in pediatric pneumonia. Respiratory Medicine 2011; 105: 1939-1945.

Esposito S, Molteni CG, Daleno C, Valzano A, Fossali E, Da Dalt L, Cecinati V, Bruzzese E, Giacchino R, Giaquinto C, Lackenby A, Principi N. Clinical and socioeconomic impact of different types and subtypes of seasonal influenza viruses in children during influenza seasons 2007/2008 and 2008/2009. BMC Infectious Diseases 2011; 11: 271.

Rizzo C, Esposito S, Azzari C, Bartolozzi G, Fara GM, Lo Giudice M, Ciofi Degli Atti M; Italian Society of Pediatric Allergy, Immunology. West Nile Virus infections in children: a disease pediatricians should think about. Pediatric Infectious Disease Journal 2011; 30:65-6.

Capaccio P, Clemente IA, Mantovani M, Marchisio P, Esposito S, Pignataro L. Submental dermoid cyst: a rare clinical entity in early pediatric age. Pediatria Medica Chirurgica 2011; 33: 92-94.

Esposito S, Selicorni A, Daleno C, Valzano A, Cerutti M, Galeone C, Consolo S, Menni F, Principi N. Immunogenicity, safety and tolerability of monovalent 2009 pandemic influenza A/H1N1 MF59-adjuvanted vaccine in children and adolescents with Williams or Cornelia De Lange syndrome. Human Vaccines 2011; 7: 613–617.

Esposito S, Daleno C, Tagliabue C, Scala A, Picciolli I, Taroni F, Galeone C, Baldanti F, Principi N. Antibody response of healthy children to pandemic A/H1N1/2009 influenza virus. Virology Journal 2011; 8: 563.

Chiappini E, Galli L, Lisi C, Gabiano C, Giaquinto C, Giacomet V, Buffolano W, Esposito S, Badolato R, Berbardi S, Cellini M, Dodi I, Faldella G, Osimani P, Genovese O, Nicastro E, Viscoli C, Salvini F, Tovo PA, Maurizio de M, Italian Register for HIV Infection in Children. Risk of perinatal HIV infection in infants born in Italy to immigrant mothers. Clinical Infectious Diseases 2011; 53: 310-313.

Cardinale F, Chironna M, Dumke R, Binetti A, Daleno C, Sallustio A, Valzano A, Esposito S. Macrolide-resistant Mycoplasma pneumoniae in paediatric pneumonia. European Respiratory Journal 2011; 37: 1522-1524.

Esposito S, Bosis S, Dusi E, Cinnante C, Principi N. Brain abscess due to Streptococcus intermedius in a 3-year-old child. Pediatrics International 2011; 53: 1104-1105.

 IF: 255

 Collaborazioni  nazionali

 con Università

Università degli Studi di Pavia, Università degli Studi di Padova, Università degli Studi di Verona, Università degli Studi del Piemonte Orientale di Novara, Università di Bologna, Università degli Studi di Parma, Università Federico II di Napoli

 con Fondazione

Istituto Nazionale di Genetica Molecolare (INGM), Milano; Istituto di ricerca Ospedale Giannina Gaslini, Genova; Ospedale Bambino Gesù, Roma

 con Istituto di ricerca

 con Altro

Istituto Superiore di Sanità, Roma; Regione Lombardia, Milano

 Collaborazioni internazionali

 con Università

UT Southwestern Medical Center (TX, USA); University of Texas Medical Branch, Galveston (TX, USA);’Università di Oxford, Oxford (UK); St George's Hospital Medical School,Londra (UK); Erasmus Medical Center, Rotterdam (The Netherlands); University of Heidelberg, Heidelberg (Germany)

 con Fondazione

PENTA Foundation; European Society for Pediatric Infectious Diseases (ESPID);  European Society for Clinical Microbiology and Infectious Diseases (ESCMID)

 con Istituto di ricerca

Health Protection Agency, Londra (UK),

 

 con Altro

World Health Organization (WHO), European Medicine Agency (EMA), European Center for Disease Control (ECDC)

 Finanziamenti

 2013

 Fonte Ministero del Lavoro, della Salute

 e delle Politiche Sociali

 Fonte IRCCS

 Fonte Europa…

 Fonte Industria

 Fonte Fondazioni

 Altro…

 Euro 600.000

 

 Euro 282.260

 Euro…….……

 Euro 100.000

 Euro 70.000

 Euro…….……

 Finanziamenti

 2012

 Fonte Ministero…

 Fonte IRCCS

 Fonte Europa

 Fonte Industria

 Fonte Fondazioni

 Altro…

 Euro…….……

 Euro 247.650

 Euro 15.000

 Euro 430.000

 Euro 50.000

 Euro…….……

 Finanziamenti

 2011

 Fonte Ministero del Lavoro, della Salute

 e delle Politiche Sociali

 Fonte IRCCS

 Fonte Europa

 Fonte Industria

 Fonte Fondazioni

 Altro…

 Euro 600.000

 

 Euro 240.000

 Euro 350.000

 Euro 250.000

 Euro 30.000

 Euro…….……

 

 

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